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ORIGINAL ARTICLE
Year : 2016  |  Volume : 6  |  Issue : 1  |  Page : 5-10

Endoscopic nasopharyngectomy for nasopharyngeal carcinoma


1 Professor of Otorhinolaryngology, Faculty of Medicine, Cairo University, Kasr Alainy Medical School, Garden City, Cairo, Dean's Office, Egypt
2 Professor of Clinical Oncology, Faculty of Medicine, Cairo University, Kasr Alainy Medical School, Garden City, Cairo, Dean's Office, Egypt
3 Lecturer of Otorhinolaryngology, Faculty of Medicine, Cairo University, Kasr Alainy Medical School, Garden City, Cairo, Dean's Office, Egypt

Correspondence Address:
Reda Hussien Kamel
Professor of Otorhinolaryngology, Faculty of Medicine, Cairo University, 00201222137172 Kasr Alainy Medical School, Garden City, Cairo, Dean's Office
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2090-7540.186904

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Background The radiosensitivity of nasopharyngeal carcinoma has led to effective primary treatment using radiation with or without chemotherapy. Despite modern radiotherapy techniques, recurrent or persistent disease remains challenging. Materials and Methods This study included 10 patients who underwent endoscopic nasopharyngectomy: two primary cases of nasopharyngeal carcinoma, five cases recurrent after finishing treatment with chemoradiation by 7–14 months, and three patients showed residual disease just after finishing therapy using chemoradiotherapy confirmed with biopsy. The average age was 43.5 years. Chemoradiotherapy was performed postoperatively for all patients. Margin status and complications were evaluated. Repeated nasopharyngeal endoscopic assessment plus computed tomography and MRI imaging with contrast were carried out, with a mean follow-up period of 17.5 months. Results One patient showed recurrence (10%) and was managed with resurgery. No deaths were recorded due to the disease (overall survival rate, 100%) until the end of this study, and there were no major complications. Conclusion Endoscopic nasopharyngectomy is a feasible, direct, effective, and safe surgical procedure. Long-term follow-up is necessary for better assessment.


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